Klinickopatologické aspekty a diferenciální diagnóza Lynchova syndromu

Lynch syndrome (LS), formerly known as hereditary nonpolyposis colorectal cancer (HNPCC) is a familial cancer syndrome with an autosomal dominant inheritance pattern. Its genetic basis is most commonly a germline mutation in one of the mismatch repair (MMR) genes, that are responsible for correction...

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Bibliographic Details
Main Author: Dušek, Martin
Other Authors: Daum, Ondřej
Format: Doctoral Thesis
Language:Czech
Published: 2017
Online Access:http://www.nusl.cz/ntk/nusl-368397