Klinickopatologické aspekty a diferenciální diagnóza Lynchova syndromu
Lynch syndrome (LS), formerly known as hereditary nonpolyposis colorectal cancer (HNPCC) is a familial cancer syndrome with an autosomal dominant inheritance pattern. Its genetic basis is most commonly a germline mutation in one of the mismatch repair (MMR) genes, that are responsible for correction...
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Format: | Doctoral Thesis |
Language: | Czech |
Published: |
2017
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Online Access: | http://www.nusl.cz/ntk/nusl-368397 |