Vliv onemocnění v dětském věku na výskyt alergií

• Main Author: Kotrchová, Veronika
• Other Authors: Jílek, Petr
• Format: Dissertation
• Language: Czech
• Published: 2014
• Online Access: http://www.nusl.cz/ntk/nusl-342225

Author: Veronika Kotrchová Title: The effect of the diseases in infancy on the prevelance of allergies in children Diploma work Charles University in Prague, Faculty of Pharmacy in Hradec Králové, study program Pharmacy Background: To find out if diseases in infancy are protective or risk factors for prevelance of allergy. We interested mainly in infectious diseases. We compared our results with so called Hygiene hypothesis, which claims that contact with microbes in early childhood boosts immature immune system due to activation of Treg lymphocytes. Methods: We sent 2793 questionnaires to 69 elementary schools all over the Czech republic. 1697 of them returned to us. We defined two groups of respondents allergics and non-allergics. For categorization we used specific criterions. According to these criterions 420 respondents were named as allergic and 774 respondents as non-alergic. For better identification if concrete disease played role as protective or risk factor for development of allergy, we chose another specific criterions. Results: We didn't prove any statistical significance between diseases in infancy and the later prevelance of allergies except for bronchitis. According to our results bronchitis in first year of life played role as risk factor for development of allergic symptoms after...