Vývoj rezistence na antibiotika Neisseria gonorrhoeae ve FN Brno

• Main Author: Brabencová, Sylva
• Other Authors: Paterová, Pavla
• Format: Dissertation
• Language: Czech
• Published: 2013
• Online Access: http://www.nusl.cz/ntk/nusl-322104

Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Biological and medical Sciences Candidate: Bc. Sylva Brabencová Supervisor: MUDr. Pavla Paterová Consultant: MUDr. Jana Juránková, Ph.D. Title of diploma thesis: The development of antibiotic resistance of Neisseria gonorrhoeae in University Hospital Brno This thesis deals about the bacteria Neisseria gonorrhoeae (N. gonorrhoeae), agents of sexually transmitted disease gonorrhea. In the first part there are basic characteristics of the bacteria and its growth, virulence factors, mechanisms of resistance and its diagnostic options and also its ability to develop an antibiotic resistance, pathogenesis of disease, its progress and symptoms and, ultimately, treatment options of disease. Practical part contains a basic process of an income of clinical sample, a laboratory culture, an izolation of strains and possibilities of a biochemical identification and an antibiotic susceptibility testing. There are also the statistical informations obtained from the Department of Clinical Microbiology at the University Hospital Brno sice the year 1998 to 2012. They are arranged into a tabular and graphical form, showing increased incidence of disease in the population, especially in men. They shows distribution incidence of disease...