Vlastnosti a použití parenterálních přípravků

• Main Author: Kotásková, Denisa
• Other Authors: Šklubalová, Zdeňka
• Format: Dissertation
• Language: Czech
• Published: 2012
• Online Access: http://www.nusl.cz/ntk/nusl-307090

Charles University in Prague, Faculty of Pharmacy in Hradci Králové Department of: Pharmaceutical Technology Consultant: Doc. PharmDr. Šklubalová Zdeňka, Ph.D. Student: Denisa Kotásková Title of Thesis: Properties and the employment of parenteral preparations. This thesis presents parenteral preparations. The aim of thesis was introduction of injection and infusion preparations, which are the most commonly used parenteral drug forms. The emphasis is placed on the complete list of excipients which are essential ingredients because they ensure the safety and efficacy of this formulation and positively influence its properties. The essential pharmacopoeial quality requirements are shortly discussed, such as sterility, non-pyrogenity, the absence of particulate matter, nominal volume or airtight containers. The largest part of the thesis is focused on the use of the parenteral infusion. It deals primarily with the use of electrolyte solutions in the treatment of disorders of the inner body balance. The important chapter is the parenteral nutrition, which includes the most important nutrients such as carbohydrates, amino acids and microheterogenous oil emulsions. The peritoneal dialysis solution and the plasmaexpander solution are the supplement of this thesis. The thesis also attends to the production...