Statistické metody pro interpretaci forenzních DNA směsí

In the present work we study interpretation of forensic DNA evidence from the point of view of probability theory and mathematical statistics. We provide a detailed mathematical formalization of the problem, which enables us to formulate mathematically accurate and consistent results. We deal with e...

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Bibliographic Details
Main Author: Kubátová, Helena
Other Authors: Zvárová, Jana
Format: Dissertation
Language:Czech
Published: 2010
Online Access:http://www.nusl.cz/ntk/nusl-298936
Description
Summary:In the present work we study interpretation of forensic DNA evidence from the point of view of probability theory and mathematical statistics. We provide a detailed mathematical formalization of the problem, which enables us to formulate mathematically accurate and consistent results. We deal with evaluation of a given evidence in terms of a likelihood ratio, which compares two hypotheses speci ed by genotypes of known contributors and the number of unknown contributors to the DNA mixture. We further analyze the case of a subdivided population, performing a thorough revision of the formulas for homozygous and heterozygous genotypes, their general version and a theorem for calculating the probability that an assumed number of random individuals explain a given genetic evidence.