Stanovení plasticity u mannitolu

• Main Author: Votava, Jakub
• Other Authors: Špaček, Vladimír
• Format: Dissertation
• Language: Czech
• Published: 2008
• Online Access: http://www.nusl.cz/ntk/nusl-295500

The visco-elastic characteristics and knowledge of them are the important factors that influence pressability of materials. These characteristics differ for every material and it is possible to determine them by variety of methods. In our thesis (chapter Experiments) we evaluated the relationship "force - travel" and determined elasticity and plasticity of materials. The test of relaxation of tense is another way to determine plasticity of materials. The results are parameters of FminA, FminB, FPL and parameters of single-parametric equation that describes decrease of preassure in a tablet during the relaxation period. These parameters and their evaluation are the goal of this thesis. We determined the Young's modulus of elasticity from the tablet dilatation measure restults. The value of Young's modulus of elasticity for mannitol is 413,36 MPa. The value of total plasticity Pc is 91,34177 MPa.s. Generally: increasing value of total plasticity determines increase of tablet material pressability.