Využití separačních metod v analýze léčiv II
Employment of separation methods in the field of drug analysis II Diploma Thesis Markéta Ferebauerová Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Chemistry and Drug Control This diploma thesis summarizes findings of both drug analysis done by gas...
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Online Access: | http://www.nusl.cz/ntk/nusl-282968 |
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ndltd-nusl.cz-oai-invenio.nusl.cz-2829682017-06-27T04:41:04Z Využití separačních metod v analýze léčiv II Employment of separation methods in the field of drug analysis II. Kastner, Petr Ferebauerová, Markéta Kučera, Radim Employment of separation methods in the field of drug analysis II Diploma Thesis Markéta Ferebauerová Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Chemistry and Drug Control This diploma thesis summarizes findings of both drug analysis done by gas chromatography and validation of analytical method. The mixture of glycerol, 1,3-butanediol and two other substances was studied. Specifity, linearity, precision and accuracy were studied and verified. In terms of robustness, the following parameters of the method were changed: the flow rate of carier gas, spit ratio, carier gas, stability of the sample, the temperature of detector, the temperature of injection port and the temperature of column. Further, the author demonstrate that the method is mostly influenced by the flow rate of carier gas and the temperature of column of the first part. Finally,the 24-hour stability of the sample was confirmed. 2009 info:eu-repo/semantics/masterThesis http://www.nusl.cz/ntk/nusl-282968 cze info:eu-repo/semantics/restrictedAccess |
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Czech |
format |
Dissertation |
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NDLTD |
description |
Employment of separation methods in the field of drug analysis II Diploma Thesis Markéta Ferebauerová Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Chemistry and Drug Control This diploma thesis summarizes findings of both drug analysis done by gas chromatography and validation of analytical method. The mixture of glycerol, 1,3-butanediol and two other substances was studied. Specifity, linearity, precision and accuracy were studied and verified. In terms of robustness, the following parameters of the method were changed: the flow rate of carier gas, spit ratio, carier gas, stability of the sample, the temperature of detector, the temperature of injection port and the temperature of column. Further, the author demonstrate that the method is mostly influenced by the flow rate of carier gas and the temperature of column of the first part. Finally,the 24-hour stability of the sample was confirmed. |
author2 |
Kastner, Petr |
author_facet |
Kastner, Petr Ferebauerová, Markéta |
author |
Ferebauerová, Markéta |
spellingShingle |
Ferebauerová, Markéta Využití separačních metod v analýze léčiv II |
author_sort |
Ferebauerová, Markéta |
title |
Využití separačních metod v analýze léčiv II |
title_short |
Využití separačních metod v analýze léčiv II |
title_full |
Využití separačních metod v analýze léčiv II |
title_fullStr |
Využití separačních metod v analýze léčiv II |
title_full_unstemmed |
Využití separačních metod v analýze léčiv II |
title_sort |
využití separačních metod v analýze léčiv ii |
publishDate |
2009 |
url |
http://www.nusl.cz/ntk/nusl-282968 |
work_keys_str_mv |
AT ferebauerovamarketa vyuzitiseparacnichmetodvanalyzelecivii AT ferebauerovamarketa employmentofseparationmethodsinthefieldofdruganalysisii |
_version_ |
1718469230034157568 |