Transkarbam 12 a transdermální průnik kofeinu z oleokrémů. 2.
In theoretical part of this work, the skin barrier function and transdermal permeation enhancers (with focus on Transkarbam 12, T12) were reviewed. In following experimental part, the acceleration effect of various concentrations of Transkarbam 12 (T12) on in vitro caffeine permeation through full-t...
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| Format: | Dissertation |
| Language: | Czech |
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2009
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| Online Access: | http://www.nusl.cz/ntk/nusl-282929 |
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ndltd-nusl.cz-oai-invenio.nusl.cz-282929 |
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ndltd-nusl.cz-oai-invenio.nusl.cz-2829292017-06-27T04:41:04Z Transkarbam 12 a transdermální průnik kofeinu z oleokrémů. 2. Transkarbam 12 and caffeine transdermal permeation from oleocreams. 2. Doležal, Pavel Dvořáková, Pavla Berka, Pavel In theoretical part of this work, the skin barrier function and transdermal permeation enhancers (with focus on Transkarbam 12, T12) were reviewed. In following experimental part, the acceleration effect of various concentrations of Transkarbam 12 (T12) on in vitro caffeine permeation through full-thickness pig ear skin was evaluated. Caffeine was administered in oleocreams containing 30 % aqueous phase. The values of mean flux of caffeine Jr from creams containing 0%; 0,3%; 0,5%; 0,7% and 1% T12 were 6,29 ± 0,90 μg.cm-2.h-1; 9,13 ± 0,95 μg.cm-2.h-1; 8,71 ± 1,91 μg.cm 2.h-1; 10,20 ± 3,25 μg.cm-2.h-1 and 7,06 ± 0,81 μg.cm-2.h-1 respectively. Keywords: Transkarbam 12, transdermal permeation enhancers, caffeine, oleocream 2009 info:eu-repo/semantics/masterThesis http://www.nusl.cz/ntk/nusl-282929 cze info:eu-repo/semantics/restrictedAccess |
| collection |
NDLTD |
| language |
Czech |
| format |
Dissertation |
| sources |
NDLTD |
| description |
In theoretical part of this work, the skin barrier function and transdermal permeation enhancers (with focus on Transkarbam 12, T12) were reviewed. In following experimental part, the acceleration effect of various concentrations of Transkarbam 12 (T12) on in vitro caffeine permeation through full-thickness pig ear skin was evaluated. Caffeine was administered in oleocreams containing 30 % aqueous phase. The values of mean flux of caffeine Jr from creams containing 0%; 0,3%; 0,5%; 0,7% and 1% T12 were 6,29 ± 0,90 μg.cm-2.h-1; 9,13 ± 0,95 μg.cm-2.h-1; 8,71 ± 1,91 μg.cm 2.h-1; 10,20 ± 3,25 μg.cm-2.h-1 and 7,06 ± 0,81 μg.cm-2.h-1 respectively. Keywords: Transkarbam 12, transdermal permeation enhancers, caffeine, oleocream |
| author2 |
Doležal, Pavel |
| author_facet |
Doležal, Pavel Dvořáková, Pavla |
| author |
Dvořáková, Pavla |
| spellingShingle |
Dvořáková, Pavla Transkarbam 12 a transdermální průnik kofeinu z oleokrémů. 2. |
| author_sort |
Dvořáková, Pavla |
| title |
Transkarbam 12 a transdermální průnik kofeinu z oleokrémů. 2. |
| title_short |
Transkarbam 12 a transdermální průnik kofeinu z oleokrémů. 2. |
| title_full |
Transkarbam 12 a transdermální průnik kofeinu z oleokrémů. 2. |
| title_fullStr |
Transkarbam 12 a transdermální průnik kofeinu z oleokrémů. 2. |
| title_full_unstemmed |
Transkarbam 12 a transdermální průnik kofeinu z oleokrémů. 2. |
| title_sort |
transkarbam 12 a transdermální průnik kofeinu z oleokrémů. 2. |
| publishDate |
2009 |
| url |
http://www.nusl.cz/ntk/nusl-282929 |
| work_keys_str_mv |
AT dvorakovapavla transkarbam12atransdermalniprunikkofeinuzoleokremu2 AT dvorakovapavla transkarbam12andcaffeinetransdermalpermeationfromoleocreams2 |
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