Summary: | 1. Abstract A poisoning in humans by vegetable products Michaela Havlásková Faculty of Pharmacy Charles University in Prague Abstract The thesis deals with human poisonings by substances of alkaloid and glycoside types contained in plants. The total of 184 cases was found, of which 171 related to alkaloids and 13 to glycosides. The cases were monitored worldwide in the period of 2001 - 2009. They included both intoxications with the intention of murder or suicide, and without any intention occurred due to negligence or ignorance or poisonings for the purpose of misuse of a plant. Alkaloids and glycosides were divided to individual groups. The highest number of poisonings in the field of alkaloids occurred at the group of tropane alkaloids with the total number of 98 cases, of which 50 were caused by Deadly nightshade (Atropa belladonna L.), 21 by Jimson weed (Datura L.), 23 by Black henbane (Hyoscyamus niger L.) and 1 by Belladona (Scopolia L.). Individual cases provide information on the sex and age of a patient, symptoms and treatment. The highest number of cases of intoxication by glycosides was detected with cardio-active glycosides with the total number of 7 cases, of which 4 were caused by Oleander (Nerium oleander L.), 2 by Yellow oleander (Thevetia neriifolia L.) and 1 by Foxglove (Digitalis lanata...
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