Využití molekulárně biologických in vitro metod pro interpretaci mechanizmů vybraných lékových interakcí warfarinu
Xenobiotics are metabolized by hepatic biotransformation enzymes of cytochrome P450. Drug-drug interactions, where one substance increases the activity of biotransformation enzymes involved in the metabolism of other drug and accelerate its elimination, often occure in xenobiotics metabolism. The pr...
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Format: | Dissertation |
Language: | Czech |
Published: |
2009
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Online Access: | http://www.nusl.cz/ntk/nusl-279062 |