Využití molekulárně biologických in vitro metod pro interpretaci mechanizmů vybraných lékových interakcí warfarinu

Xenobiotics are metabolized by hepatic biotransformation enzymes of cytochrome P450. Drug-drug interactions, where one substance increases the activity of biotransformation enzymes involved in the metabolism of other drug and accelerate its elimination, often occure in xenobiotics metabolism. The pr...

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Bibliographic Details
Main Author: Rulcová, Alice
Other Authors: Pávek, Petr
Format: Dissertation
Language:Czech
Published: 2009
Online Access:http://www.nusl.cz/ntk/nusl-279062