Izolace a charakterizace nového antimikrobiálního peptidu (defenzinu) exprimovaného v klíštěti obecném \kur{Ixodes ricinus}

Izolace a charakterizace nového antimikrobiálního peptidu (defenzinu) exprimovaného v klíštěti obecném \kur{Ixodes ricinus}

Ticks are important blood feeding arthropod vectors of different pathogens. Control of tick-borne pathogens is complicated due to a lack of vaccines. Development of the novel methods of tick control and search of the new vaccine candidates are required for suppression of tick populations and for con...

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Main Author: KEPLOVÁ, Nelly
Format: Dissertation
Language:Czech
Published: 2016
Online Access:http://www.nusl.cz/ntk/nusl-204544
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spelling ndltd-nusl.cz-oai-invenio.nusl.cz-2045442018-10-04T14:36:23Z Izolace a charakterizace nového antimikrobiálního peptidu (defenzinu) exprimovaného v klíštěti obecném \kur{Ixodes ricinus} KEPLOVÁ, Nelly Ticks are important blood feeding arthropod vectors of different pathogens. Control of tick-borne pathogens is complicated due to a lack of vaccines. Development of the novel methods of tick control and search of the new vaccine candidates are required for suppression of tick populations and for control of tick-borne infectious diseases. Among possible candidates, defensins are espicially interesting. In this study, a novel anionic Ixodes ricinus defensin named AnIrDef is described, and its antimicrobial activity in vitro is confirmed. Due to the similarity with defensins from other ticks, it is assumed that I. ricinus AnIrDef is involved in the defence against microbes from bloodmeals. 2016 info:eu-repo/semantics/masterThesis http://www.nusl.cz/ntk/nusl-204544 cze info:eu-repo/semantics/restrictedAccess
collection NDLTD
language Czech
format Dissertation
sources NDLTD
description Ticks are important blood feeding arthropod vectors of different pathogens. Control of tick-borne pathogens is complicated due to a lack of vaccines. Development of the novel methods of tick control and search of the new vaccine candidates are required for suppression of tick populations and for control of tick-borne infectious diseases. Among possible candidates, defensins are espicially interesting. In this study, a novel anionic Ixodes ricinus defensin named AnIrDef is described, and its antimicrobial activity in vitro is confirmed. Due to the similarity with defensins from other ticks, it is assumed that I. ricinus AnIrDef is involved in the defence against microbes from bloodmeals.
author KEPLOVÁ, Nelly
spellingShingle KEPLOVÁ, Nelly
Izolace a charakterizace nového antimikrobiálního peptidu (defenzinu) exprimovaného v klíštěti obecném \kur{Ixodes ricinus}
author_facet KEPLOVÁ, Nelly
author_sort KEPLOVÁ, Nelly
title Izolace a charakterizace nového antimikrobiálního peptidu (defenzinu) exprimovaného v klíštěti obecném \kur{Ixodes ricinus}
title_short Izolace a charakterizace nového antimikrobiálního peptidu (defenzinu) exprimovaného v klíštěti obecném \kur{Ixodes ricinus}
title_full Izolace a charakterizace nového antimikrobiálního peptidu (defenzinu) exprimovaného v klíštěti obecném \kur{Ixodes ricinus}
title_fullStr Izolace a charakterizace nového antimikrobiálního peptidu (defenzinu) exprimovaného v klíštěti obecném \kur{Ixodes ricinus}
title_full_unstemmed Izolace a charakterizace nového antimikrobiálního peptidu (defenzinu) exprimovaného v klíštěti obecném \kur{Ixodes ricinus}
title_sort izolace a charakterizace nového antimikrobiálního peptidu (defenzinu) exprimovaného v klíštěti obecném \kur{ixodes ricinus}
publishDate 2016
url http://www.nusl.cz/ntk/nusl-204544
work_keys_str_mv AT keplovanelly izolaceacharakterizacenovehoantimikrobialnihopeptidudefenzinuexprimovanehovklistetiobecnemkurixodesricinus
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