The implementation of laboratory investigations for diagnosing pyruvate kinase deficiency at the Johannesburg Hospital

ABSTRACT Pyruvate kinase is an essential enzyme in the anaerobic glycolytic pathway of the erythrocyte. The clinical presentation of this enzyme deficiency is due to the haemolytic process that results from the inability of erythrocytes to generate sufficient ATP. Although pyruvate kinase and gl...

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Bibliographic Details
Main Author: Durand, Pierre Marcel
Format: Others
Language:en
Published: 2008
Subjects:
Online Access:http://hdl.handle.net/10539/4950