The implementation of laboratory investigations for diagnosing pyruvate kinase deficiency at the Johannesburg Hospital
ABSTRACT Pyruvate kinase is an essential enzyme in the anaerobic glycolytic pathway of the erythrocyte. The clinical presentation of this enzyme deficiency is due to the haemolytic process that results from the inability of erythrocytes to generate sufficient ATP. Although pyruvate kinase and gl...
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Format: | Others |
Language: | en |
Published: |
2008
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Online Access: | http://hdl.handle.net/10539/4950 |