Aspects of high-level trimethoprin resistance in gram-negative bacteria isolated in South Africa

A thesis submitted to the Faculty of Medicine, University of the Witwatersrand, Johannesburg, in fulfilment of the requirements of Doctor of Philosophy. Johannesburg 1991 === Trimethoprim is a broad-spectrum antimicrobial agent frequently used either in combination with sulphamethoxazole (cotrimoxa...

Full description

Bibliographic Details
Main Author: Wylie, Barbara A
Format: Others
Language:en
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10539/25842
id ndltd-netd.ac.za-oai-union.ndltd.org-wits-oai-wiredspace.wits.ac.za-10539-25842
record_format oai_dc
spelling ndltd-netd.ac.za-oai-union.ndltd.org-wits-oai-wiredspace.wits.ac.za-10539-258422019-05-11T03:42:06Z Aspects of high-level trimethoprin resistance in gram-negative bacteria isolated in South Africa Wylie, Barbara A Trimethoprim Resistance Gram-Negative Bacteria South Africa A thesis submitted to the Faculty of Medicine, University of the Witwatersrand, Johannesburg, in fulfilment of the requirements of Doctor of Philosophy. Johannesburg 1991 Trimethoprim is a broad-spectrum antimicrobial agent frequently used either in combination with sulphamethoxazole (cotrimoxazole) or alone in the treatment of urinary and respiratory tract infections. Since the introduction of this drug in 1969 resistance to it has been monitored in several centres in Europe continuously but only intermittently in the United States of America and developing countries in Africa, Asia, Central and South America. In Europe the incidence of trimethoprim resistance has increased significantly in the last 20 years. In developing countries no trends have been established but the incidence of resistance appears to be greater in these countries than in Europe or the USA. IT2018 2018-10-17T13:24:17Z 2018-10-17T13:24:17Z 1991-02-07 Thesis https://hdl.handle.net/10539/25842 en application/pdf
collection NDLTD
language en
format Others
sources NDLTD
topic Trimethoprim Resistance
Gram-Negative Bacteria
South Africa
spellingShingle Trimethoprim Resistance
Gram-Negative Bacteria
South Africa
Wylie, Barbara A
Aspects of high-level trimethoprin resistance in gram-negative bacteria isolated in South Africa
description A thesis submitted to the Faculty of Medicine, University of the Witwatersrand, Johannesburg, in fulfilment of the requirements of Doctor of Philosophy. Johannesburg 1991 === Trimethoprim is a broad-spectrum antimicrobial agent frequently used either in combination with sulphamethoxazole (cotrimoxazole) or alone in the treatment of urinary and respiratory tract infections. Since the introduction of this drug in 1969 resistance to it has been monitored in several centres in Europe continuously but only intermittently in the United States of America and developing countries in Africa, Asia, Central and South America. In Europe the incidence of trimethoprim resistance has increased significantly in the last 20 years. In developing countries no trends have been established but the incidence of resistance appears to be greater in these countries than in Europe or the USA. === IT2018
author Wylie, Barbara A
author_facet Wylie, Barbara A
author_sort Wylie, Barbara A
title Aspects of high-level trimethoprin resistance in gram-negative bacteria isolated in South Africa
title_short Aspects of high-level trimethoprin resistance in gram-negative bacteria isolated in South Africa
title_full Aspects of high-level trimethoprin resistance in gram-negative bacteria isolated in South Africa
title_fullStr Aspects of high-level trimethoprin resistance in gram-negative bacteria isolated in South Africa
title_full_unstemmed Aspects of high-level trimethoprin resistance in gram-negative bacteria isolated in South Africa
title_sort aspects of high-level trimethoprin resistance in gram-negative bacteria isolated in south africa
publishDate 2018
url https://hdl.handle.net/10539/25842
work_keys_str_mv AT wyliebarbaraa aspectsofhighleveltrimethoprinresistanceingramnegativebacteriaisolatedinsouthafrica
_version_ 1719085163143495680