| Summary: | A thesis submitted to the Faculty of Medicine,
University of the Witwatersrand, for the
degree of Doctor of Philosophy in Medicine. === Despite having been initially described more than fifty
years ago, sclerotherapy of oesophageal varices has only
relatively recently became regarded as one of the primary
modalities both to control bleeding oesophageal varices and
to prevent recurrent bleeding. Sclerotherapy, however, ts
associated with numerous complications and its exact
mechanism of action, particularly that pertaining to its
effect on haemostasis, has to date been poorly
documented. One of the problems of comparing the various
trials has been the diversity of both the technique and the
type and concentration of the sclerosants used. (Abbreviation abstract) === Andrew Chakane 2018
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