Construction and screening of a DNA library to detect integrated hepatitis B virus DNA

Degree awarded with distinction on 6 December l995. A dissertation submitted to the Faculty of Science, University the Witwatersrand, in fulfilment of the requirements for the degree of Master of Science. March. 1995 === Hepatitis B virus (HBV) infection resulting in integration of the viral DNA...

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Main Author: Bondonno, Catherine Patricia
Format: Others
Language:en
Published: 2016
Subjects:
Online Access:http://hdl.handle.net/10539/20873
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spelling ndltd-netd.ac.za-oai-union.ndltd.org-wits-oai-wiredspace.wits.ac.za-10539-208732019-05-11T03:40:12Z Construction and screening of a DNA library to detect integrated hepatitis B virus DNA Bondonno, Catherine Patricia Hepatitis B virus. DNA -- Research. DNA fingerprinting. Degree awarded with distinction on 6 December l995. A dissertation submitted to the Faculty of Science, University the Witwatersrand, in fulfilment of the requirements for the degree of Master of Science. March. 1995 Hepatitis B virus (HBV) infection resulting in integration of the viral DNA into host liver cell DNA is associated with the development of hepatocellular carcinoma (HCC). This is indicated by epidemiological trends, molecular studies and studies of animal models infected with viruses closely related to HBv. However, little is known about the mechanism by which the integrated HBV DNA includes HCC despite continuing analysis of the integrated HBV DNA and its surrounding cellular sequences. [Abbreviated Abstract. Open document to view full version] 2016-08-16T13:02:21Z 2016-08-16T13:02:21Z 2016-08-16 Thesis http://hdl.handle.net/10539/20873 en application/pdf
collection NDLTD
language en
format Others
sources NDLTD
topic Hepatitis B virus.
DNA -- Research.
DNA fingerprinting.
spellingShingle Hepatitis B virus.
DNA -- Research.
DNA fingerprinting.
Bondonno, Catherine Patricia
Construction and screening of a DNA library to detect integrated hepatitis B virus DNA
description Degree awarded with distinction on 6 December l995. A dissertation submitted to the Faculty of Science, University the Witwatersrand, in fulfilment of the requirements for the degree of Master of Science. March. 1995 === Hepatitis B virus (HBV) infection resulting in integration of the viral DNA into host liver cell DNA is associated with the development of hepatocellular carcinoma (HCC). This is indicated by epidemiological trends, molecular studies and studies of animal models infected with viruses closely related to HBv. However, little is known about the mechanism by which the integrated HBV DNA includes HCC despite continuing analysis of the integrated HBV DNA and its surrounding cellular sequences. [Abbreviated Abstract. Open document to view full version]
author Bondonno, Catherine Patricia
author_facet Bondonno, Catherine Patricia
author_sort Bondonno, Catherine Patricia
title Construction and screening of a DNA library to detect integrated hepatitis B virus DNA
title_short Construction and screening of a DNA library to detect integrated hepatitis B virus DNA
title_full Construction and screening of a DNA library to detect integrated hepatitis B virus DNA
title_fullStr Construction and screening of a DNA library to detect integrated hepatitis B virus DNA
title_full_unstemmed Construction and screening of a DNA library to detect integrated hepatitis B virus DNA
title_sort construction and screening of a dna library to detect integrated hepatitis b virus dna
publishDate 2016
url http://hdl.handle.net/10539/20873
work_keys_str_mv AT bondonnocatherinepatricia constructionandscreeningofadnalibrarytodetectintegratedhepatitisbvirusdna
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