Inactivation of hepatitis B virus CCCDNA using engineered transcription activator-like affector nucleases

Hepatitis B virus (HBV) is a major global public health burden, with over 350 million people chronically infected. This results in approximately 600,000 liver cancer-related deaths annually. Chronic HBV infections are normally managed with long-term anti-HBV therapeutics, such as reverse transcripti...

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Bibliographic Details
Main Author: Bloom, Kristie Michelle
Format: Others
Language:en
Published: 2014
Subjects:
Online Access:http://hdl.handle.net10539/14420