The interaction of focal adhesion kinase with apoptotic regulators underpins anoikis resistance in human oesophageal carcinoma
Aberrant communication between survival signalling- and cell death pathways enables tumour cells to resist anoikis - the subset of apoptosis triggered by loss of cell-extracellular matrix (ECM) contact. Focal adhesion kinase (FAK) has been implicated as the key intermediate in the acquisition of ano...
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Format: | Others |
Language: | en |
Published: |
2011
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Online Access: | http://hdl.handle.net/10539/10310 |