Molecular dynamic simulation studies of the South African HIV-1 Integrase subtype C protein to understand the structural impact of naturally occurring polymorphisms

>Magister Scientiae - MSc === The viral Integrase (IN) protein is an essential enzyme of all known retroviruses, including HIV-1. It is responsible for the insertion of viral DNA into the human genome. It is known that HIV-1 is highly diverse with a high mutation rate as evidenced by the presence...

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Bibliographic Details
Main Author: Isaacs, Darren Mathew
Other Authors: Cloete, Ruben Earl Ashley
Language:en
Published: University of Western Cape 2021
Subjects:
Online Access:http://hdl.handle.net/11394/8365

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