Synthesis of DMSO based silver nanoparticles for application in wound healing

• Main Author: Nqakala, Zimkhitha Biancah
• Other Authors: Onani, M.O
• Language: en
• Published: University of Western Cape 2021
• Subjects: Cellular uptake; Cytotoxicity; Dimethyl sulfoxide; Membrane mitochondrial potential; Nanotechnology
• Online Access: http://hdl.handle.net/11394/8233

>Magister Scientiae - MSc === Silver nanoparticles (AgNPs) apart from being chemically significant, have shown a lot of health benefits, the most studied being their anti-bacterial and anti-inflammatory properties. These biological properties can be further enhanced by adding compounds with known medical properties giving rise to even more desired potent materials. Anti-bacterial and cytotoxicity studies show that these AgNPs can kill bacteria, prevent infections and regenerate skin cells. On the other hand, previous studies have reported dimethyl sulfoxide (DMSO) with attractive wound healing abilities specifically cell growth promotion. It was then envisaged that the combination of DMSO and AgNPs could lead to a potent wound healing agent. It is a well-known fact that non-healing wounds pose a socioeconomic threat to a large population worldwide. === 2023