Factors influencing adherence to antiretroviral treatment in the Queenstown region Eastern Cape (South Africa)

Magister Curationis - MCur === BACKGROUND: Failure to adhere to antiretroviral therapy (ART) has negative consequences not only for patients themselves, but for health systems. Strict adherence to ART therapy together with modified life style will result in a positive outcome (WHO, 2003a). AIM: The...

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Bibliographic Details
Main Author: Magadla, Nobuhle
Other Authors: Chipps, Jennifer
Language:en
Published: University of the Western Cape 2018
Online Access:http://hdl.handle.net/11394/5840
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Summary:Magister Curationis - MCur === BACKGROUND: Failure to adhere to antiretroviral therapy (ART) has negative consequences not only for patients themselves, but for health systems. Strict adherence to ART therapy together with modified life style will result in a positive outcome (WHO, 2003a). AIM: The aim of the study was to describe factors that may influence adherence to ART treatment. METHOD: A quantitative research approach was used to conduct a survey using an interviewer administered questionnaire in the Queenstown region in three clinics with patients on ART. A random sample of 118 was selected out of a possible 594 patients. The response rate was n=97 (80.5%). The majority were females, n=77 (79%) with most of the respondents being 35-44 years, n=46 (47.4%) and single, n=76 (78%). Social and economic results: Respondents were economically inactive (unemployed), n= 49 (50, 5%) and n=40 (41.2%) on disability grant with no significant association between the employment status and acceptance of antiretroviral treatment. Males had higher rates for acceptance of ART and with more males n= 8/20 (40%) as compared to women n= 13/77 (16.8%) stating that they accepted their outcome (X2=5, p=.035). High levels of emotional support were reported n= 79 (81.4%). HEALTH CARE SERVICE RESULTS: Only n=3 (3.1%) of the respondents reported to have their own transport, resulting in 72 respondents (74.2%) reporting that it was difficult to comply with treatment if they lived far from the clinic. CONDITION RELATED RESULTS: Only n= 17 (17.5%) respondents reported that they suffered from OIs in the last six months with Diarrhoea being the most common n= 93 (94.9%). Patient related results: Only 7 respondents reported to take alcohol at an average of 1.4 bottles a week. About n=81 (83.5%) of respondents reported difficulty in taking treatment at work. TREATMENT RELATED RESULTS: The majority of respondents n= 43 (44.3%) reported to be on their current regiment for less than a year. Almost 100% of the respondents had correct knowledge of their treatment regimen and prescriptions for OIs and ART therapy. Most of the respondents (90.7%) agreed with the statement, that HIV patient's family should facilitates their intake of medication and this was significantly higher in respondents who have not accepted their diagnosis and the need to be on medication for the rest of their lives. CONCLUSION: Treatment adherence management should take into consideration the factors that may influence adherence