Identification and characterisation of a novel gene, DWNN, isolated from promoter-trapped Chinese hamster ovary cells

Identification and characterisation of a novel gene, DWNN, isolated from promoter-trapped Chinese hamster ovary cells

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Philosophiae Doctor - PhD === The process of cytotoxic T lymphocyte (CTL) killing involves the recognition and destruction of foreign antigens by cytotoxic T cells and is of crucial importance to the defence of the organism against viral infections. Defects in this process can lead to various autoim...

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Bibliographic Details
Main Author: Skepu, Amanda
Other Authors: Rees, D.J.G.
Language:en
Published: University of the Western Cape 2013
Subjects:
Apoptosis
Cell death
Pathology
Cellular
Online Access:http://hdl.handle.net/11394/2244
Description
Summary:Philosophiae Doctor - PhD === The process of cytotoxic T lymphocyte (CTL) killing involves the recognition and destruction of foreign antigens by cytotoxic T cells and is of crucial importance to the defence of the organism against viral infections. Defects in this process can lead to various autoimmune diseases and cancer. The aim of this study was to identify more genes involved in the cell death pathway and to link CTL killing, apoptosis and cancer. === South Africa

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