Identification and characterisation of a novel gene, DWNN, isolated from promoter-trapped Chinese hamster ovary cells.

<p>The process of cytotoxic T lymphocyte (CTL) killing involves the recognition and destruction of foreign antigens by cytotoxic T cells and is of crucial importance to the defence of the organism against viral infections. Defects in this process can lead to various autoimmune diseases and can...

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Bibliographic Details
Main Author: Skepu, Amanda.
Format: Others
Language:English
Published: 2005
Subjects:
Online Access:http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_7576_1249626665
Description
Summary:<p>The process of cytotoxic T lymphocyte (CTL) killing involves the recognition and destruction of foreign antigens by cytotoxic T cells and is of crucial importance to the defence of the organism against viral infections. Defects in this process can lead to various autoimmune diseases and cancer. The aim of this study was to identify more genes involved in the cell death pathway and to link CTL killing, apoptosis and cancer.</p>