In vitro P-glycoprotein activity of alkaloid-enriched fractions from Solanum aculeastrum and its synergistic potential with doxorubicin
Cancer is one of the most life-threatening groups of diseases that affect humanity. Current treatment options include surgery, radiation treatment as well as chemotherapeutic agents such as alkylating agents, antimetabolites and antimitotic antibiotics. Resistance is often experienced due to overexp...
Main Author: | Burger, Trevor Michael |
---|---|
Other Authors: | Cordier, Werner |
Language: | en |
Published: |
2016
|
Subjects: | |
Online Access: | http://hdl.handle.net/2263/56952 Burger, TM 2016, In vitro P-glycoprotein activity of alkaloid-enriched fractions from Solanum aculeastrum and its synergistic potential with doxorubicin, MSc Dissertation, University of Pretoria, Pretoria, viewed yymmdd <http://hdl.handle.net/2263/56952> |
Similar Items
-
Solamargine, a bioactive steroidal alkaloid isolated from Solanum aculeastrum induces non-selective cytotoxicity and P-glycoprotein inhibition
by: Trevor Burger, et al.
Published: (2018-05-01) -
<b>A novel glycosidic steroidal alkaloid from <i>Solanum aculeastrum</i></b>
by: Sumesh C. Chhabra, et al.
Published: (2003-06-01) -
Effect of processing on the efficacy and safety of Solanum Aculeastrum Dunal berries
by: Aboyade, Oluwaseyi Mayode
Published: (2009) -
Experimental therapeutic studies of Solanum aculeastrum Dunal. on Leishmania major infection in BALB/c mice
by: Linet T Laban, et al.
Published: (2015-01-01) -
Antimycoplasmal Activities of Compounds from Solanum aculeastrum and Piliostigma thonningii against Strains from the Mycoplasma mycoides Cluster
by: Francisca Kama-Kama, et al.
Published: (2017-12-01)