Characterisation of BRCA1 genomic rearrangements in South African breast and/or ovarian cancer families

Characterisation of BRCA1 genomic rearrangements in South African breast and/or ovarian cancer families

Germ-line mutations within the breast cancer susceptibility genes, BRCA1 and BRCA2 are responsible for inherited susceptibility to breast and ovarian cancer. A wide spectrum of pathogenic mutations has been identified within both genes, but alterations within these genes occur far less frequently th...

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Bibliographic Details
Main Author: Reeves, Michelle Diana
Other Authors: Prof E Jansen van Rensburg
Published: 2013
Subjects:
Brca1
Breast cancer
Ovarian cancer
UCTD
Online Access:http://hdl.handle.net/2263/29071
Reeves, MD 2006, Characterisation of BRCA1 genomic rearrangements in South African breast and/or ovarian cancer families, MSc dissertation, University of Pretoria, Pretoria, viewed yymmdd < http://hdl.handle.net/2263/29071 >
http://upetd.up.ac.za/thesis/available/etd-10262011-085600/

Internet

http://hdl.handle.net/2263/29071
Reeves, MD 2006, Characterisation of BRCA1 genomic rearrangements in South African breast and/or ovarian cancer families, MSc dissertation, University of Pretoria, Pretoria, viewed yymmdd < http://hdl.handle.net/2263/29071 >
http://upetd.up.ac.za/thesis/available/etd-10262011-085600/

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