Kinetic analysis of a recombinantly expressed Plasmodium falciparum dihydrofolate synthase-folylpolyglutamate synthase

Malaria is a life-threatening parasitic disease that causes at least 300 million acute illnesses annually, of which at least one million infected humans die, mainly children under the age of 5 years. This overwhelming burden is due to the most virulent causative agent, Plasmodium falciparum, as a re...

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Bibliographic Details
Main Author: Human, Esmare
Other Authors: Louw, Abraham Izak
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/2263/25829
http://upetd.up.ac.za/thesis/available/etd-06252008-093616/