| Summary: | The use of plants with molluscicidal properties IS a simple, inexpensive and
appropriate technology for focal control of the snail vector.
Isolation and identification of the active constituents is essential for the study of their
toxicities and stabilities under field conditions, for dosage purposes, for structureactivity
investigations and for effects on snail metabolism or physiology. It is in this
context, that an investigation into molluscicides and other compounds from
indigenous plants has been carried out.
From Apodytesdimidiata subsp. dimidiata, betulinic acid (53) genipin (49) and
lO-acetyl genipin (58) have been isolated and the last two have proved to possess
molluscicidal activity. Furthermore, 4-ethylcatechol (60) isolated from Gardenia
thunbergia is one of the most powerful naturally-occurring molluscicides. === Thesis (M.Sc.)-University of Natal, Pietermatizburg, 1996.
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