Chemiese transformasies van koolhidrate met behulp van oorgangsmetaalreagense
D.Sc. (Chemistry) === The aim of this study was directed towards the stereo- and regiospecific introduction of carbon nucleophiles onto the 1- and 4-positions of glycopyranosides, since these chiral molecules contain the tetrahidropyran skeleton of a wide range of biologically active compounds (exam...
| Main Author: | |
|---|---|
| Published: |
2015
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/10210/14738 |
| Summary: | D.Sc. (Chemistry) === The aim of this study was directed towards the stereo- and regiospecific introduction of carbon nucleophiles onto the 1- and 4-positions of glycopyranosides, since these chiral molecules contain the tetrahidropyran skeleton of a wide range of biologically active compounds (example the carpenter bee pheromone or the civit cat pheromone) or substructures of more complex natural products, such as the ionophore antibiotics indanomycin and zincophorin. Two appraoches for the introduction of carbon substituents onto the 1- and/or 4-positions of unsaturated glycopyranosides were investigated ... |
|---|