THE SYNTHESIS OF AN INTERNAL STANDARD FOR BICALUTAMIDE
(R,S)-Bicalutamide [N-(4-cyano-3-trifluoromethylphenyl)-α-methyl-α-hydroxy-β-(4- fluorophenylsulfonyl)propanamide], sold as Casodex®, is the leading antiandrogen currently used to treat prostate cancer. It binds to androgen receptors and blocks cancer growth. This work aims to develop internal s...
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Format: | Others |
Language: | en-uk |
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University of the Free State
2009
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Online Access: | http://etd.uovs.ac.za//theses/available/etd-04082009-151002/restricted/ |