Synthesis and biological activity of ajoenes with increased aqueous solubility
The synthesis of four new ajoene analogues is presented in this thesis. The key to the synthesis was gaining access to a phenol derivative containing the ajoene core structure (sulfoxide / vinyl disulfide) that could be functionalised with various substituents. Evaluation of biological activity retu...
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| Format: | Dissertation |
| Language: | English |
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University of Cape Town
2014
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| Online Access: | http://hdl.handle.net/11427/6674 |