Thermodynamic properties of diamino-diamide ligand as potential anti-inflammatory agent
Includes bibliographical references. === It has been found that low molecular mass copper(II) complexes are effective in the treatment of rheumatoid) arthritis (RA). Increasing the amount of copper associated with low molecular mass ligands in plasma helps to alleviate the symptoms of rheumatoid art...
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Online Access: | http://hdl.handle.net/11427/6355 |
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ndltd-netd.ac.za-oai-union.ndltd.org-uct-oai-localhost-11427-63552020-10-06T05:11:07Z Thermodynamic properties of diamino-diamide ligand as potential anti-inflammatory agent Odisitse, Sebusi Jackson, Graham Ellis Chemistry Includes bibliographical references. It has been found that low molecular mass copper(II) complexes are effective in the treatment of rheumatoid) arthritis (RA). Increasing the amount of copper associated with low molecular mass ligands in plasma helps to alleviate the symptoms of rheumatoid arthritis. Low molecular weight ligand, 3,5-bis[(aminoethyl)ethanediamideJ-4-oxahexacyclododecane (PCUA) was investigated using glass electrode potentiometry, UV/Visible spectroscopy, nuclear magnetic resonance spectroscopy, speciation modelling as well as blood plasma modelling. 2014-08-13T14:29:24Z 2014-08-13T14:29:24Z 2003 Master Thesis Masters MSc http://hdl.handle.net/11427/6355 eng application/pdf University of Cape Town Faculty of Science Department of Chemistry |
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NDLTD |
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English |
format |
Dissertation |
sources |
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Chemistry |
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Chemistry Odisitse, Sebusi Thermodynamic properties of diamino-diamide ligand as potential anti-inflammatory agent |
description |
Includes bibliographical references. === It has been found that low molecular mass copper(II) complexes are effective in the treatment of rheumatoid) arthritis (RA). Increasing the amount of copper associated with low molecular mass ligands in plasma helps to alleviate the symptoms of rheumatoid arthritis. Low molecular weight ligand, 3,5-bis[(aminoethyl)ethanediamideJ-4-oxahexacyclododecane (PCUA) was investigated using glass electrode potentiometry, UV/Visible spectroscopy, nuclear magnetic resonance spectroscopy, speciation modelling as well as blood plasma modelling. |
author2 |
Jackson, Graham Ellis |
author_facet |
Jackson, Graham Ellis Odisitse, Sebusi |
author |
Odisitse, Sebusi |
author_sort |
Odisitse, Sebusi |
title |
Thermodynamic properties of diamino-diamide ligand as potential anti-inflammatory agent |
title_short |
Thermodynamic properties of diamino-diamide ligand as potential anti-inflammatory agent |
title_full |
Thermodynamic properties of diamino-diamide ligand as potential anti-inflammatory agent |
title_fullStr |
Thermodynamic properties of diamino-diamide ligand as potential anti-inflammatory agent |
title_full_unstemmed |
Thermodynamic properties of diamino-diamide ligand as potential anti-inflammatory agent |
title_sort |
thermodynamic properties of diamino-diamide ligand as potential anti-inflammatory agent |
publisher |
University of Cape Town |
publishDate |
2014 |
url |
http://hdl.handle.net/11427/6355 |
work_keys_str_mv |
AT odisitsesebusi thermodynamicpropertiesofdiaminodiamideligandaspotentialantiinflammatoryagent |
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1719348846330380288 |