Thermodynamic properties of diamino-diamide ligand as potential anti-inflammatory agent
Includes bibliographical references. === It has been found that low molecular mass copper(II) complexes are effective in the treatment of rheumatoid) arthritis (RA). Increasing the amount of copper associated with low molecular mass ligands in plasma helps to alleviate the symptoms of rheumatoid art...
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| Format: | Dissertation |
| Language: | English |
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University of Cape Town
2014
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| Online Access: | http://hdl.handle.net/11427/6355 |
| Summary: | Includes bibliographical references. === It has been found that low molecular mass copper(II) complexes are effective in the treatment of rheumatoid) arthritis (RA). Increasing the amount of copper associated with low molecular mass ligands in plasma helps to alleviate the symptoms of rheumatoid arthritis. Low molecular weight ligand, 3,5-bis[(aminoethyl)ethanediamideJ-4-oxahexacyclododecane (PCUA) was investigated using glass electrode potentiometry, UV/Visible spectroscopy, nuclear magnetic resonance spectroscopy, speciation modelling as well as blood plasma modelling. |
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