Development of new methodologies for functionalizing glycals and 1,2-cyclopropanated sugars, and applications in the synthesis of inhibitors of enzymes in the Mycobacteria
Includes bibliographical references (p. 177-186). === Tuberculosis (TB) is a contagious respiratory disease caused by Mycobacterium tuberculosis. Due to lack of an efficient and short-term treatment of TB, the bacterium has become resistant to the first line antibiotics and the disease has ranked ne...
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Format: | Doctoral Thesis |
Language: | English |
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University of Cape Town
2014
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Online Access: | http://hdl.handle.net/11427/6318 |