Characterisation of the metabolome of Mycobacterium tuberculosis to identify new pathways and pathway holes
Includes abstract. === Includes bibliographical references. === Due to high incidence rates and the development of new drug-resistant or multidrug-resistant strains of TB, the development of new medicines and treatments for tuberculosis is a necessity. In order to develop these drugs, Mycobacterium...
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| Format: | Dissertation |
| Language: | English |
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University of Cape Town
2014
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| Online Access: | http://hdl.handle.net/11427/5971 |
| Summary: | Includes abstract. === Includes bibliographical references. === Due to high incidence rates and the development of new drug-resistant or multidrug-resistant strains of TB, the development of new medicines and treatments for tuberculosis is a necessity. In order to develop these drugs, Mycobacterium tuberculosis (Mtb) needs to be studied more completely; this study performs a characterisation of the metabolome of Mtb and comparison across the phylogenetic profile to identify notable pathways. |
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