Investigating the role of growth hormone receptor in oesophageal squamous-cell carcinoma.
Includes abstract. === Includes bibliographical references. === Squamous-cell carcinoma of the oesophagus is a formidable disease which poses a significant health risk in developing countries where incidence is high and survival is low. Investigating the poorly understood mechanisms involved in oeso...
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| Format: | Dissertation |
| Language: | English |
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University of Cape Town
2014
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| Online Access: | http://hdl.handle.net/11427/3413 |
| Summary: | Includes abstract. === Includes bibliographical references. === Squamous-cell carcinoma of the oesophagus is a formidable disease which poses a significant health risk in developing countries where incidence is high and survival is low. Investigating the poorly understood mechanisms involved in oesophageal tumourigenesis may provide a platform to develop improved diagnostic techniques and therapies. The growth hormone (GH) signalling axis is important for proper cellular and organ system function. The axis has been shown to play a role in a number of cancers. |
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