Investigation of DNA methylation at the promoter region of the aralkylamine N-acetyltransferase (AANAT ) gene in South African children with Autism Spectrum Disorder
Sleep problems and suppressed melatonin production commonly presents with core Autism Spectrum Disorder (ASD) traits. Aralkylamine N-acetyltransferase (AANAT) acts as the penultimate and rate-limiting enzyme in the melatonin biosynthetic pathway, and a study by Hu et al. (2009) reported that AANAT e...
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| Format: | Dissertation |
| Language: | English |
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University of Cape Town
2018
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| Online Access: | http://hdl.handle.net/11427/27555 |