One Health-One City; the extent of Shiga-toxin producing Escherichia coli in Cape Town

One Health-One City; the extent of Shiga-toxin producing Escherichia coli in Cape Town

The estimated global burden of STEC (Shiga toxin producing Escherichia coli) is 2,481,511 illnesses, 269 deaths, and 26,827 DALYs with 48% of these being foodborne. This thesis provides information on STEC diagnostic strategy, undetected STEC in a tertiary referral hospital in Cape Town, and the vir...

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Bibliographic Details
Main Author: Kalule, John Bosco
Other Authors: Nicol, Mark P
Format: Doctoral Thesis
Language:English
Published: University of Cape Town 2018
Subjects:
Medical Microbiology
Online Access:http://hdl.handle.net/11427/26938
Description
Summary:The estimated global burden of STEC (Shiga toxin producing Escherichia coli) is 2,481,511 illnesses, 269 deaths, and 26,827 DALYs with 48% of these being foodborne. This thesis provides information on STEC diagnostic strategy, undetected STEC in a tertiary referral hospital in Cape Town, and the virulence and antimicrobial resistance properties of tellurite resistant diarrheic E. coli isolated on CHROMagar(TM)STEC (CHROMagar Microbiology, Paris, France). Deploying the One - Health surveillance approach to study selected diarrheic bacterial pathogens in an informal settlement setting, this study sheds light on the extent of bacterial foodborne pathogens in human and non-human sources.

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