Regulation of melanogenesis in conditionally immortalised mouse melanocytes expressing a temperature-sensitive SV40 large T antigen
The transformation of a normal melanocyte to a malignant melanoma involves a series of poorly understood genotypic and phenotypic alterations. In vitro models of melanoma formation generated by transforming mouse melanocytes with exogenous oncogenes have revealed that this process is frequently acco...
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| Format: | Doctoral Thesis |
| Language: | English |
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University of Cape Town
2018
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| Online Access: | http://hdl.handle.net/11427/26787 |