Mechanistic insights into the cancer cell cytotoxicity and blood stability of the garlic compound ajoene
Ajoene, a garlic-derived natural product and its structural analogues are strongly cytotoxic to cancer cells. These compounds are however known to exhibit low blood stability and erythrocyte toxicity. This thesis reports on the synthesis of eight ajoene analogues designed to probe structure-activity...
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| Format: | Dissertation |
| Language: | English |
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University of Cape Town
2017
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| Online Access: | http://hdl.handle.net/11427/22989 |