The impact of sexually transmitted infections and inflammation in the female genital tract and blood on susceptibility to HIV-1 infection and disease progression

Background. In sub-Saharan Africa, which has the highest prevalence of HIV-1 worldwide, most newHIV-1 infections occur by sexual transmission to women. Recent studies in non-human primates have demonstrated that pro-inflammatory cytokine production in the genital tract is necessary for immune cell r...

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Bibliographic Details
Main Author: Masson, Lindi
Other Authors: Passmore, Jo-Ann
Format: Doctoral Thesis
Language:English
Published: University of Cape Town 2016
Subjects:
HIV
Online Access:http://hdl.handle.net/11427/18609