The role of IL-4 and Th2-like cytokines in pulmonary tuberculosis

The role of IL-4 and Th2-like cytokines in pulmonary tuberculosis

Includes bibliographical references === Tuberculosis (TB) vaccine candidates have been mostly ineffective and it remains unclear as to what constitutes protective host immunity. Despite high levels of IFN-γ at the site of disease, the Th1 cytokine associated with protection, many individuals still h...

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Bibliographic Details
Main Author: Pooran, Anil
Other Authors: Dheda, Keertan
Format: Doctoral Thesis
Language:English
Published: University of Cape Town 2016
Subjects:
Medicine
Online Access:http://hdl.handle.net/11427/16784
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spelling ndltd-netd.ac.za-oai-union.ndltd.org-uct-oai-localhost-11427-167842020-07-22T05:08:06Z The role of IL-4 and Th2-like cytokines in pulmonary tuberculosis Pooran, Anil Dheda, Keertan Blackburn, Jonathan Medicine Includes bibliographical references Tuberculosis (TB) vaccine candidates have been mostly ineffective and it remains unclear as to what constitutes protective host immunity. Despite high levels of IFN-γ at the site of disease, the Th1 cytokine associated with protection, many individuals still have progressive active TB. Whether a Th2-like immune response (IL-4; IL-4δ2; IL-9) can subvert protective host immunity requires clarification. 2016-02-05T07:23:42Z 2016-02-05T07:23:42Z 2015 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/16784 eng application/pdf University of Cape Town Faculty of Health Sciences Department of Medicine
collection NDLTD
language English
format Doctoral Thesis
sources NDLTD
topic Medicine
spellingShingle Medicine
Pooran, Anil
The role of IL-4 and Th2-like cytokines in pulmonary tuberculosis
description Includes bibliographical references === Tuberculosis (TB) vaccine candidates have been mostly ineffective and it remains unclear as to what constitutes protective host immunity. Despite high levels of IFN-γ at the site of disease, the Th1 cytokine associated with protection, many individuals still have progressive active TB. Whether a Th2-like immune response (IL-4; IL-4δ2; IL-9) can subvert protective host immunity requires clarification.
author2 Dheda, Keertan
author_facet Dheda, Keertan
Pooran, Anil
author Pooran, Anil
author_sort Pooran, Anil
title The role of IL-4 and Th2-like cytokines in pulmonary tuberculosis
title_short The role of IL-4 and Th2-like cytokines in pulmonary tuberculosis
title_full The role of IL-4 and Th2-like cytokines in pulmonary tuberculosis
title_fullStr The role of IL-4 and Th2-like cytokines in pulmonary tuberculosis
title_full_unstemmed The role of IL-4 and Th2-like cytokines in pulmonary tuberculosis
title_sort role of il-4 and th2-like cytokines in pulmonary tuberculosis
publisher University of Cape Town
publishDate 2016
url http://hdl.handle.net/11427/16784
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