FMRI guided DTI at the grey-white matter interface : with application to a connectivity analysis of the default mode network in Urbach-Wiethe disease

• Main Author: Baasch, Roland
• Other Authors: Spottiswoode, Bruce Shawn
• Format: Dissertation
• Language: English
• Published: University of Cape Town 2015
• Subjects: Biomedical Engineering
• Online Access: http://hdl.handle.net/11427/12246

Includes abstract. === Includes bibliographical references. === The cerebral cortex is composed of a thin layer of Grey Matter (GM), functionally subdivided into discrete regions which are connected in a large scale network via White Matter (WM) tracts. With fMRI (Functional Magnetic Resonance Imaging) it is possible to identify cortical regions involved in specific tasks, and with DTI (Diffusion Tensor Imaging) the structural connections between these areas can be mapped. The aim of this thesis is to to identify and track only those WM tracts entering and leaving a GM Region Of Interest (ROI) defined by fMRI.