The regulation of type I collagen gene expression in stromal fibroblast by breast tumour cells

Includes abstract. === Includes bibliographical references (leaves 110-135). === Recent studies have revealed that interactions between tumour cells and the surrounding stroma play an important role in facilitating tumour growth and invasion. Stromal fibroblasts produce most of the extracellular mat...

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Bibliographic Details
Main Author:	Rose, Beverley Ann
Other Authors:	Parker, Iqbal
Format:	Doctoral Thesis
Language:	English
Published:	University of Cape Town 2015
Subjects:	Medical Biochemistry
Online Access:	http://hdl.handle.net/11427/10861

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spelling	ndltd-netd.ac.za-oai-union.ndltd.org-uct-oai-localhost-11427-108612020-07-22T05:07:52Z The regulation of type I collagen gene expression in stromal fibroblast by breast tumour cells Rose, Beverley Ann Parker, Iqbal Leaner, Virna Medical Biochemistry Includes abstract. Includes bibliographical references (leaves 110-135). Recent studies have revealed that interactions between tumour cells and the surrounding stroma play an important role in facilitating tumour growth and invasion. Stromal fibroblasts produce most of the extracellular matrix (ECM) components found in the stroma, including type I collagen. Previous in vivo studies in our laboratory have shown that type I collagen mRNA levels are decreased in stage II and III breast tumour tissue compared to adjacent normal tissue. 2015-01-01T12:43:06Z 2015-01-01T12:43:06Z 2011 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/10861 eng application/pdf University of Cape Town Faculty of Health Sciences Division of Medical Biochemistry
collection	NDLTD
language	English
format	Doctoral Thesis
sources	NDLTD
topic	Medical Biochemistry
spellingShingle	Medical Biochemistry Rose, Beverley Ann The regulation of type I collagen gene expression in stromal fibroblast by breast tumour cells
description	Includes abstract. === Includes bibliographical references (leaves 110-135). === Recent studies have revealed that interactions between tumour cells and the surrounding stroma play an important role in facilitating tumour growth and invasion. Stromal fibroblasts produce most of the extracellular matrix (ECM) components found in the stroma, including type I collagen. Previous in vivo studies in our laboratory have shown that type I collagen mRNA levels are decreased in stage II and III breast tumour tissue compared to adjacent normal tissue.
author2	Parker, Iqbal
author_facet	Parker, Iqbal Rose, Beverley Ann
author	Rose, Beverley Ann
author_sort	Rose, Beverley Ann
title	The regulation of type I collagen gene expression in stromal fibroblast by breast tumour cells
title_short	The regulation of type I collagen gene expression in stromal fibroblast by breast tumour cells
title_full	The regulation of type I collagen gene expression in stromal fibroblast by breast tumour cells
title_fullStr	The regulation of type I collagen gene expression in stromal fibroblast by breast tumour cells
title_full_unstemmed	The regulation of type I collagen gene expression in stromal fibroblast by breast tumour cells
title_sort	regulation of type i collagen gene expression in stromal fibroblast by breast tumour cells
publisher	University of Cape Town
publishDate	2015
url	http://hdl.handle.net/11427/10861
work_keys_str_mv	AT rosebeverleyann theregulationoftypeicollagengeneexpressioninstromalfibroblastbybreasttumourcells AT rosebeverleyann regulationoftypeicollagengeneexpressioninstromalfibroblastbybreasttumourcells
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The regulation of type I collagen gene expression in stromal fibroblast by breast tumour cells

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