Effect of concentration and degree of saturation of topical fluocinonide formulations on in vitro membrane transport and in vivo availability on human skin
Purpose. The thermodynamic acitvity of drugs in topical vehicles is considered to significantly influence topical delivery. In vitro diffusion across a synthetic membrane was shown to be correlated to the degree of saturation of the drug in the applied vehicle and therefore offers a potential for in...
| Main Authors: | , , , , |
|---|---|
| Format: | Others |
| Language: | English |
| Published: |
1999
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| Online Access: | http://hdl.handle.net/10962/d1006560 |