The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3

The effects of agitation rate, buffer molarity,and mesh size on the dissolution rate of verapamil hydrochloride from sustained release matrix tablets were studied using USP Apparatus 3. Eudragit® and Carbopol® were used as rate-retarding polymers in tablets prepared by wet granulation.The study was...

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Main Authors: Khamanga, S M M, Walker, Roderick
Format: Others
Language:English
Published: 2007
Online Access:http://hdl.handle.net/10962/d1006307
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spelling ndltd-netd.ac.za-oai-union.ndltd.org-rhodes-vital-63862018-12-11T04:30:21ZThe effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3Khamanga, S M MWalker, RoderickThe effects of agitation rate, buffer molarity,and mesh size on the dissolution rate of verapamil hydrochloride from sustained release matrix tablets were studied using USP Apparatus 3. Eudragit® and Carbopol® were used as rate-retarding polymers in tablets prepared by wet granulation.The study was conducted to determine whether the drugs exhibit similar release characteristics when tested under the same dissolution conditions. It was found that the dissolution rate of verapamil hydrochloride was affected by the variables assessed in these studies.2007textArticle5 pagespdfvital:6386http://hdl.handle.net/10962/d1006307English
collection NDLTD
language English
format Others
sources NDLTD
description The effects of agitation rate, buffer molarity,and mesh size on the dissolution rate of verapamil hydrochloride from sustained release matrix tablets were studied using USP Apparatus 3. Eudragit® and Carbopol® were used as rate-retarding polymers in tablets prepared by wet granulation.The study was conducted to determine whether the drugs exhibit similar release characteristics when tested under the same dissolution conditions. It was found that the dissolution rate of verapamil hydrochloride was affected by the variables assessed in these studies.
author Khamanga, S M M
Walker, Roderick
spellingShingle Khamanga, S M M
Walker, Roderick
The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3
author_facet Khamanga, S M M
Walker, Roderick
author_sort Khamanga, S M M
title The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3
title_short The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3
title_full The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3
title_fullStr The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3
title_full_unstemmed The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3
title_sort effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using usp apparatus 3
publishDate 2007
url http://hdl.handle.net/10962/d1006307
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