The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3
The effects of agitation rate, buffer molarity,and mesh size on the dissolution rate of verapamil hydrochloride from sustained release matrix tablets were studied using USP Apparatus 3. Eudragit® and Carbopol® were used as rate-retarding polymers in tablets prepared by wet granulation.The study was...
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ndltd-netd.ac.za-oai-union.ndltd.org-rhodes-vital-63862018-12-11T04:30:21ZThe effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3Khamanga, S M MWalker, RoderickThe effects of agitation rate, buffer molarity,and mesh size on the dissolution rate of verapamil hydrochloride from sustained release matrix tablets were studied using USP Apparatus 3. Eudragit® and Carbopol® were used as rate-retarding polymers in tablets prepared by wet granulation.The study was conducted to determine whether the drugs exhibit similar release characteristics when tested under the same dissolution conditions. It was found that the dissolution rate of verapamil hydrochloride was affected by the variables assessed in these studies.2007textArticle5 pagespdfvital:6386http://hdl.handle.net/10962/d1006307English |
collection |
NDLTD |
language |
English |
format |
Others
|
sources |
NDLTD |
description |
The effects of agitation rate, buffer molarity,and mesh size on the dissolution rate of verapamil hydrochloride from sustained release matrix tablets were studied using USP Apparatus 3. Eudragit® and Carbopol® were used as rate-retarding polymers in tablets prepared by wet granulation.The study was conducted to determine whether the drugs exhibit similar release characteristics when tested under the same dissolution conditions. It was found that the dissolution rate of verapamil hydrochloride was affected by the variables assessed in these studies. |
author |
Khamanga, S M M Walker, Roderick |
spellingShingle |
Khamanga, S M M Walker, Roderick The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3 |
author_facet |
Khamanga, S M M Walker, Roderick |
author_sort |
Khamanga, S M M |
title |
The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3 |
title_short |
The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3 |
title_full |
The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3 |
title_fullStr |
The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3 |
title_full_unstemmed |
The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3 |
title_sort |
effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using usp apparatus 3 |
publishDate |
2007 |
url |
http://hdl.handle.net/10962/d1006307 |
work_keys_str_mv |
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