Synthetic, spectrometric and computer modelling studies of novel ATP analogues

This study has been concerned with the design and synthesis of A TP analogues with the potential to act as inhibitors of glutamine synthetase - a novel target for therapeutic intervention in the treatment of tuberculosis. Using a structural -analogy approach, various 3-indolylalkanoic acid, benzimid...

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Bibliographic Details
Main Author: Gxoyiya, Babalwa Siliziwe Blossom
Format: Others
Language:English
Published: Rhodes University 2008
Subjects:
Online Access:http://hdl.handle.net/10962/d1005051