Using bioinformatics tools to screen for trypanosomal cathepsin B cysteine protease inhibitors from the SANCDB as a novel therapeutic modality against Human African Trypanosomiasis (HAT)
Human African Trypanosomiasis (HAT), also known as sleeping sickness, is a fatal chronic disease that is caused by flagellated protozoans, Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense. HAT is spread by a bite from an infected tsetse fly of the Glosina genus. Up to 60 million peopl...
Main Author: | Mokhawa, Gaone |
---|---|
Format: | Others |
Language: | English |
Published: |
Rhodes University
2016
|
Online Access: | http://hdl.handle.net/10962/3304 |
Similar Items
-
Investigation of Novel Cathepsin S Cysteine Protease inhibitors
by: 史德芬
Published: (2007) -
Anti-trypanosomal activity of non-peptidic nitrile-based cysteine protease inhibitors.
by: Antonio C B Burtoloso, et al.
Published: (2017-02-01) -
Cysteine proteases as therapeutic targets: does selectivity matter? A systematic review of calpain and cathepsin inhibitors
by: Marton Siklos, et al.
Published: (2015-11-01) -
Odanacatib, a Cathepsin K Cysteine Protease Inhibitor, Kills Hookworm In Vivo
by: Jon J. Vermeire, et al.
Published: (2016-07-01) -
Cathepsin F of is a recently evolved cysteine protease
by: Sarah Sloan, et al.
Published: (2020-10-01)