In silico analysis of the effects of non-synonymous single nucleotide polymorphisms on the human macrophage migration inhibitory factor gene and their possible role in human African trypanosomiasis susceptibility

Human African trypanosomiasis (HAT) is a public health problem in sub-Saharan Africa, with approximately 10,000 cases being reported per year. The Macrophage Migration Inhibitory Factor (MIF) which is encoded by a functionally polymorphic gene is important in both innate andadaptive immune responses...

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Bibliographic Details
Main Author: Kimuda, Magambo Philip
Format: Others
Language:English
Published: Rhodes University 2016
Online Access:http://hdl.handle.net/10962/3047