Blood levels of selective antiretroviral drugs over a period of time, in Sprague-Dawley rats / Michael du Plooy

Blood levels of selective antiretroviral drugs over a period of time, in Sprague-Dawley rats / Michael du Plooy

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Selective antiretroviral! (ARV) drugs are primarily metabolized by cytochrome P450 (CYP) enzymes, characteristically predisposed to variation, and are therefore primarily responsible for ARV pharmacokinetic variability and associated drug interactions. For the majority of ARV drugs, the therapeutic...

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Bibliographic Details
Main Author:	Du Plooy, Michael
Published:	North-West University 2009
Subjects:	Antiretroviral therapy Blood levels Cytochrome P450 P-glycoprotein Metabolism variability Rats Treatment failure
Online Access:	http://hdl.handle.net/10394/2583

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