Ets-insulin-bolus calculation promotes tighter blycaemic control for type 1 diabetics / Henry Louis Townsend

• Main Author: Townsend, Henry Louis
• Published: North-West University 2009
• Subjects: Blood glucose profiles; Control performance; Ets-insulin-bolus calculator; Hypoglycaemia; Hyperglycaemia; Tight glycaemic control; Type 1 diabetics
• Online Access: http://hdl.handle.net/10394/1647

Type 1 Diabetes is a dangerous and life-long disease for which its prevalence is global. Research has shown that tight glycaemic control of this disease significantly reduces the risks of developing several life threatening diabetic complications. The Ets-Insulin-Bolus Calculator (EIBC), inspired by the Ets concept (Equivalent Teaspoon Sugar), was primarily designed to assist type I diabetics in improving their blood glucose control. The EIBC has shown to improve the average blood glucose level of type 1 diabetics. The need for this study however is to determine whether the ET!3C promotes tighter glycaemic control for type 1 diabetics based on a more-in-depth numerical analysis. With the use of the latest technology in blood glucose monitoring, the CGMS from Medtronic, mathematical models expressing and rating blood glucose control have been proposed and derived in this study. A clinical trial with type 1 diabetics has also been conducted. The use of the models together with the clinical trial results have shown that the EIBC does in fact promote tighter glycaemic control for type 1 diabetics. === Thesis (M.Ing. (Mechanical Engineering))--North-West University, Potchefstroom Campus, 2007.